Representative Publications
"Antineoplastic Agents 560. Isolation and Structure of Kitastatin 1 from an Alaskan Kitasatospora sp.," G.R. Pettit, R. Tan, R.K.Pettit, T.H. Smith, S. Feng, D.L. Doubek, L. Richert, J. Hamblin, C. Weber and J-C. Chapuis, J. Nat. Prod. 70, 1069-1072 (2007).
"Antineoplastic Agents 561. Total Synthesis of Respirantin 1a," G.R. Pettit, T.H. Smith, S. Feng, J.C. Knight, R. Tan, R.K. Pettit and P.A. Hinrichs, J. Nat. Prod. 70, 1073-1083 (2007).
"Antineoplastic Agents 550. Synthesis of 10b (S) - epipancratistatin from (+) - Narciclasine," G.R. Pettit, N. Melody, D.L. Herald, J.C. Knight and J-C. Chapuis, J. Nat. Prod. 70, 417 (2007).
"Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with those of the Parent Compound and a Proposed Binding Site on Tubulin," D.A. Dabydeen, J.C. Burnett, R.B. Bai, P. Verdier-Pinard, M.J. Yu, B.A.Littlefield, S.J.H. Hickford, G.R. Pettit, J.W. Blunt, M.H.G. Munro, R. Gussio and E.' Hamel, Molecular Pharmacology 70, 1866 (2006).
"Antineoplastic Agents 554. The Manitoba Bacterium Streptomyces sp.," G.R. Pettit, J.Du, R.K. Pettit, L.A. Richert, V. Mukku and M.S. Hoard, J. Nat. Prod 69, 804-806 (2006).
"Isolation and Structural Modification of 7-Deoxynarciclasine and 7-deoxy-trans-dihydronarciclasine," G.R. Pettit, S.A. Eastham, N. Melody, B. Orr, D.L. Herald, J. McGregor, J.C. Knight, D.L. Doubek, G.R. Pettit III, L.C. Garner and J.A. Bell, J. Nat. Prod. 69, 7-13 (2006).
"Design and Synthesis of a Potent Phorboxazole C (11-15) Acetal Analogue," A.B. Smith, T.M. Razler, R.M. Meis and G.R. Pettit, Organic Letters 8, 797-799 (2006).
"Design, Synthesis, and Biological Evaluation of Combretastatin Nitrogen-Containing Derivatives as Inhibitors of Tubulin Assembly and Vascular Targeting Agents," K.A. Monk, R. Siles, M. Hadimani, B.E. Mugabe, F. Ackley, K. Edvardsen, M.L. Trawick, C.M. Garner, M.R. Rhodes, G.R. Pettit and K.G. Pinney, BioOrg. Med. Chem. 14, 3231-3234 (2006).
"Antineoplastic Agents. 551. Isolation and Structures of Bauhiniastatins 1-4 from Baihinia purpurea," G.R. Pettit, A. Numata, C. Iwamoto, Y. Usami, T. Yamada, H. Ohishi and G.M. Cragg, J. Nat. Prod. 69, 323-327 (2006).
"Antitumor Studies of Auristatin PYE, a NovelSynthetic Derivative of Dolastatin 10," M.C. Bibby, P.A. Cooper, N.J. Millington, G.R. Pettit, and S.D. Shnyder, Clin. Cancer Res. 11, 9089S-9089S (2005).
"Investigation of the Efficacy and Mechanism of Action of Pancratistatin 3, 4-cyclic Phosphate," S.D. Shnyder, P.A. Cooper, J.J. Millington, J.H. Gill, G.R. Pettit and M.C. Bibby, Clin. Cancer Res. 11, 8971S-8971S (2005).
"Antineoplastic Agents 509. Synthesis of Sodium Fluorcombstatin Phosphate and Related 3-Halo-Stilbenes," G.R. Pettit, M.D. Minardi, H.J. Rosenberg, E. Hamel, M.C. Bibby, S.W. Martin, M.K. Jung, R.K. Pettit, T.J. Cuthbertson and J-C. Chapuis, J. Nat. Prod. 68, 1450-1458 (2005).
"In vitro and In vivo Antifungal Activities of the Marine Sponge Constituent Spongistatin 1," R.K. Pettit, S. Pon, Z.A. Cichacz, C.L. Herald, G.R. Pettit and T. Woyke, Medical Mycology 43, 453-463 (2005).
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