The JEOL GCmate (2004) gas chromatograph/mass spectrometer system is a magnetic sector instrument of reverse geometry design with a maximum of 5000 resolving power. The instrument has an m/z range up to 1000 at full accelerating voltage (2.5 kV). The instrument has a direct insertion probe which can be used with nominal m/z or high-resolution scanning or in the selected-ion-monitoring mode. The GCmate is interfaced with an Agilent 6890N GC.

JEOL GCmate possible applications:

• Exact mass measurements for composition determination of compounds such as natural products, environmental contaminants, petrochemicals and synthetic organic compounds
• GC/MS and GC/MS/MS analysis of biological markers in sedimentary rock extracts, hydrous pyrolysis products and crude oils
• Monitoring gases and isotopes at the very low end of the mass scale, for example CO and N2,as well as H+, D+, H2+, HD+
• Its high mass accuracy enables its data to be used to provide formula matches
• Analysis of Polychlorinated Biphenyls (PCBs) by High- Resolution Selected Ion Monitoring (HRSIM)
• Quantitative determination of dioxins in environmental samples by selected-ion-monitoring analyses
• Analysis of antioxidants

The JEOL LCmate (2002) is also a double-focusing reverse-geometry instrument. This instrument has a resolving power of 5000 (FWHM) and an m/z range up to 1500.The instrument has interchangeable electrospray (ESI), atmospheric pressure chemical ionization (APCI) interfaces. Samples can be introduced through a permanently installed Agilent 1100 liquid chromatograph, via flow injection, or through a syringe pump. The fast atom bombardment (FAB) ionization using direct insertion probe is also available.

JEOL LCmate possible applications:

• Accurate mass measurements for composition determination
• analysis of a wide range of polar and nonpolar compounds, such as peptide and protein handled typically in biotechnology, pharmaceuticals, metabolites, and pesticides

The ABI Mariner (1999)is a benchtop electrospray time-of flight (ESI-TOF) mass spectrometer. This instrument has a resolving power of 5,000(FWHM-full width at half maximum) and mass range up to 10,000 m/z. Samples can be introduced using a syringe pump or a disposable plastic pipette tip [“Electrospray ionization using disposable plastic pipette tips”, Sergei A. Aksyonov and Peter Williams, Rapid Commun. Mass Spectrom. 15 (2001) 1890-1891].

The Mariner possible applications:

• High-resolution mass analysis of sub-picomole quantities of proteins and other biopolymers
• Accurate mass measurement for structure determinations